ABO Blood Group System And Thyroid Disorders

 

Thyroid Gland

• Small Butterfly shaped
• Located at the base of neck
• Part of endocrine system
• hormones regulate metabolism

Thyroid Hormones

                                             Triiodothyronine T3

                                             Tetra iodothyronin or Thyroxine T4

Throid disorders

Common

About 42 Million people affected

Common Thyroid Disorders

                              Hyperthyroidism

                              Hypothyroidism

                              Euthyroid(non-thyroidal illness syndrome)

                              Goiter

ABO Blood Group Classification

used to denote presence of one, both or neither of the A and B antigen on erythrocytes

Review literature

Back in 1901, landsteiner was the first to explain the serological variations between indviduals based on their RBC Cell membrane antigens and antibodies present in plasma

Thyroid hormones being multifunctional are capable of causing morbidity in multiple ways if present in excess or in less amount.

Methodology

people were divided into 4 groups based on their blood groups

then divided into subgroups based on 

•  Hypothyroidism
•  Hyperthyroidism
•  Euthyroid status

Data was analysed using SPSS software

Reference ranges for Thyroid hormones

                                                  TSH         0.4-4.5mU/L

                                                   T4            4.6-12 ug/dl

                                                    T3            80-180 ng/dl

Frequency distribution of various Blood groups in Thyroid Disorder

Frequency Distribution of Thyroid hormone Level status amongst People with various Blood groups

Conclusion

Significant correlation exist between ABO Blood group system and Thyroid Disorders

Original Article link:

      https://medicopublication.com/index.php/ijphrd/article/download/9342/8735/17529#:~:text=Conclusion%3A%20Our%20results%20indicate%20that,A%E2%80%9D%20and%20%E2%80%9CB%E2%80%9D.

References

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doi:10.4103/2230-8210.83329